The Lloyd L. Gregory School of Pharmacy
Full Name: Edwin Santini
Associate Professor of Pharmaceutical Sciences
B.S., Interamerican University (Puerto Rico); Ph.D., Ponce School of Medicine.
In 2008, Dr. Santini joined Nova Southeastern University, Ponce Site as assistant
professor in the department of pharmaceutical sciences. He taught in the Pharm.D.
program and provided mentorship to students enrolled in the graduate program as well.
Dr. Santini was involved in many committees at the departmental and college levels,
including curriculum, admissions and recruitment. He was also able to establish and
maintain research collaborative projects with the faculty members at the Ponce School
of Medicine. In regards to research, Dr. Santini combines his expertise in behavior
neuroscience with patch-clamp electrophysiology to study the cellular mechanisms of
fear conditioning and extinction. He focuses on the infralimbic (IL) sub-region of
the medial prefrontal cortex (mPFC), a structure necessary for inhibiting conditioned
fear responses following fear extinction. He has found that fear extinction enhances
the intrinsic excitability of IL neurons. Changes in IL excitability appears to be
necessary for reducing conditioned fear, perhaps by inhibiting amygdala output. Since
extinction-based exposure psychotherapy is being used to treat post-traumatic stress
disorder (PTSD) and phobias, understanding the cellular mechanisms of extinction will
likely lead to new strategies for treating these disorders. Dr. Santini has an excellent
publication record with papers in high-impact journals in the field of behavioral
neuroscience. He joins the Gregory School of Pharmacy at PBA to pursue his passion
for teaching, research and service. Dr. Santini and his wife Vilmarie have two beautiful
daughters. They have been involved for many years in the creative arts ministry and
they look forward to continue to serve the Lord in the area of West Palm Beach, FL.
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